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Article

IsdA and IsdB antibodies protect mice against Staphylococcus aureus abscess formation and lethal challenge.

Vaccine - 31 Aug 2010

Kim Hwan Keun, DeDent Andrea, Cheng Alice G, McAdow Molly, Bagnoli Fabio, Missiakas Dominique M, Schneewind Olaf

Abstract excerpt

Staphylococcus aureus is the most frequent cause of bacteremia and hospital-acquired infection, however a vaccine that prevents staphylococcal disease is currently not available. Two sortase-anchored surface proteins, IsdA and IsdB, have been identified as subunit vaccines that, following active immunization, protect experimental animals against intravenous challenge with staphylococci. Here we investigate the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20226248
DOI: 10.1016/j.vaccine.2010.02.097
PMCID: PMC3095377

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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