Article
Molecular assessment of drug resistance in Plasmodium falciparum from Bahr El Gazal province, Sudan.
Tropical medicine & international health : TM & IH - 1 Dec 2003
Anderson Tim J C, Nair Shalini, Jacobzone Corine, Zavai Andes, Balkan Suna
Abstract excerpt
AIMS: To assess resistance to chloroquine (CQ) and sulphadoxine/pyrimethamine (SP) in a Sudanese parasite population. METHODS: Recurrent security problems in Akuem, Sudan, prevented us from conducting a classical in vivo treatment efficacy study. Instead we genotyped key mutations in the chloroquine resistance transporter (pfcrt), the multidrug resistance gene (pfmdr1), dihydrofolate reductase (dhfr) and...
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