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Article

Therapeutic efficacy of chloroquine and sequence variation in pfcrt gene among patients with falciparum malaria in central India.

Tropical medicine & international health : TM & IH - 1 Jan 2010

Bharti Praveen Kumar, Alam Mohammad Tauqeer, Boxer Robert, Shukla Man Mohan, Gautam Sant P, Sharma Yagya D, Singh Neeru

Abstract excerpt

OBJECTIVES: To assess the therapeutic efficacy of chloroquine (CQ) treatment against uncomplicated Plasmodium falciparum infections in a tribal population of central India (Madhya Pradesh) and to investigate the prevalence of mutant P. falciparum chloroquine-resistant transporter (pfcrt) gene in the parasite population. METHODS: Clinical and parasitological response was determined by in-vivo testing. For...

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Identifiers

PMID: 19912592
DOI: 10.1111/j.1365-3156.2009.02425.x

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