Article
A cross-sectional survey of Plasmodium falciparum pfcrt mutant haplotypes in the Democratic Republic of Congo.
The American journal of tropical medicine and hygiene - 1 Jun 2014
Antonia Alejandro L, Taylor Steve M, Janko Mark, Emch Michael, Tshefu Antoinette K, Meshnick Steven R
Abstract excerpt
In the Democratic Republic of the Congo (DRC), artesunate-amodiaquine is first-line therapy for falciparum malaria; little is known about the prevalence of molecular markers of parasite drug resistance. Across the DRC, we genotyped 166 parasites in Plasmodium falciparum chloroquine resistance transporter (pfcrt) using polymerase chain reaction (PCR) and sequencing. Of these parasites, 73 (44%) parasites were pure...
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