Article
p63 short isoforms are found in invasive carcinomas only and not in benign breast conditions.
Virchows Archiv : an international journal of pathology - 1 Apr 2010
de Biase Dario, Morandi Luca, Degli Esposti Roberta, Ligorio Claudia, Pession Annalisa, Foschini Maria P, Eusebi Vincenzo
Abstract excerpt
Two N-terminal isoforms characterize the p63 protein: the transactivating isoform TAp63 and the amino-terminal truncated isoform DeltaNp63. Two further N-terminal isoforms lacking exon 4 (d4TAp63 and DeltaNp73L) have been reported. Purpose of the study was to investigate the molecular expression of N-terminal p63 isoforms in benign and malignant breast tissues. Eighteen randomly selected cases of invasive breast...
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