Article
p63 expression in normal, hyperplastic and malignant breast tissues.
Breast cancer (Tokyo, Japan) - 1 Jan 2002
Wang Xiaojuan, Mori Ichiro, Tang Weihua, Nakamura Misa, Nakamura Yasushi, Sato Misako, Sakurai Takeo, Kakudo Kennichi
Abstract excerpt
BACKGROUND: p63 is a homologue of the p53 tumor suppressor gene and its protein is selectively expressed in the basal cells of a variety of epithelial tissues. It has recently been confirmed that p63 is expressed in the basal cells of normal prostate glands but not in prostatic carcinomas. Whether expression of p63 in breast correlates with tumor progression is the focus of this study. METHODS: Forty cases, which...
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