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Article

Effects of irbesartan on phenotypic alterations in monocytes and the inflammatory status of hypertensive patients with left ventricular hypertrophy.

BMC cardiovascular disorders - 20 Apr 2021

Zhang Jingsi, Yang Lina, Ding Yanchun

Abstract excerpt

BACKGROUND: Circulating monocytes and tissue macrophages play complex roles in the pathogenesis of hypertension and the resulting target organ damage. In this study, we observed alterations in the monocyte phenotype and inflammatory state of hypertensive patients with left ventricular hypertrophy (LVH) and studied the effects of irbesartan in these patients. This study might reveal a novel mechanism by which...

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Share to Anti-Inflammatory Agents
Share to Antigens, Differentiation, Myelomonocytic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antihypertensive Agents

Share to CD163 Antigen

Share to Hypertrophy, Left Ventricular

Share to Receptors, Immunologic

Share to Ventricular Function, Left

Share to Ventricular Remodeling

Source

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Identifiers

PMID: 33879070
DOI: 10.1186/s12872-021-02004-7
PMCID: PMC8056615

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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