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Article

Abnormal embryonic lymphatic vessel development in Tie1 hypomorphic mice.

Development (Cambridge, England) - 1 Apr 2010

Qu Xianghu, Tompkins Kevin, Batts Lorene E, Puri Mira, Baldwin H Scott, Baldwin Scott

Abstract excerpt

Tie1 is an endothelial receptor tyrosine kinase that is essential for development and maintenance of the vascular system; however, the role of Tie1 in development of the lymphatic vasculature is unknown. To address this question, we first documented that Tie1 is expressed at the earliest stages of lymphangiogenesis in Prox1-positive venous lymphatic endothelial cell (LEC) progenitors. LEC Tie1 expression is...

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Identifiers

PMID: 20223757
DOI: 10.1242/dev.043380
PMCID: PMC2847464

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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