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Article

ALK1 signaling regulates early postnatal lymphatic vessel development

11 Nov 2009

Abstract excerpt

In vertebrates, endothelial cells form 2 hierarchical tubular networks, the blood vessels and the lymphatic vessels. Despite the difference in their structure and function and genetic programs that dictate their morphogenesis, common signaling pathways have been recognized that regulate both vascular systems. ALK1 is a member of the transforming growth factor-beta type I family of receptors, and compelling...

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PMID: 19903896
DOI: 10.1182/blood-2009-07-235655

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