Article
Identification of a panel of ten cell surface protein antigens associated with immunotargeting of leukemias and lymphomas by peripheral blood gammadelta T cells.
Haematologica - 1 Aug 2010
Gomes Anita Q, Correia Daniel V, Grosso Ana R, Lança Telma, Ferreira Cristina, Lacerda João F, Barata João T, Silva Maria Gomes da, Silva-Santos Bruno
Abstract excerpt
BACKGROUND: Vgamma9Vdelta2 T lymphocytes are regarded as promising mediators of cancer immunotherapy due to their capacity to eliminate multiple experimental tumors, particularly within those of hematopoietic origin. However, Vgamma9Vdelta2 T-cell based lymphoma clinical trials have suffered from the lack of biomarkers that can be used as prognostic of therapeutic success. DESIGN AND METHODS: We have conducted a...
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