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Article

Effect of MDM2 SNP309 and p53 codon 72 polymorphisms on lung cancer risk and survival among non-smoking Chinese women in Singapore.

BMC cancer - 10 Mar 2010

Chua Hui Wan, Ng Daniel, Choo Serena, Lum San San, Li Huihua, Soh Li Ying, Sabapathy Kanaga, Seow Adeline

Abstract excerpt

BACKGROUND: Single nucleotide polymorphism (SNP) 309 resulting in a T or G allele in the promoter of MDM2, the negative regulator of p53, has been suggested to affect cancer predisposition and age of onset, primarily in females. However, findings have been inconsistent in various cancers, and ethnicity appears to be a critical factor influencing the effects of the SNP on cancer risk. An increasing trend has been...

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Identifiers

PMID: 20219101
DOI: 10.1186/1471-2407-10-88
PMCID: PMC2842241

Genes

MDM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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