Article
Allele-specific silencing by RNA interference.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010
Hohjoh Hirohiko
Abstract excerpt
Allele-specific gene silencing by RNA interference (RNAi) is therapeutically useful for specifically inhibiting the expression of disease-associated alleles without suppressing the expression of corresponding wild-type alleles. To realize such allele-specific RNAi (ASP-RNAi), the design and asses...
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