Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Wnt signaling in pancreatic islets.

Advances in experimental medicine and biology - 1 Jan 2010

Liu Zhengyu, Habener Joel F

Abstract excerpt

The Wnt signaling pathway is critically important not only for stem cell amplification, differentiation, and migration, but also is important for organogenesis and the development of the body plan. Beta-catenin/TCF7L2-dependent Wnt signaling (the canonical pathway) is involved in pancreas development, islet function, and insulin production and secretion. The glucoincretin hormone glucagon-like peptide-1 and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 2
Share to Insulin
Share to Insulin-Secreting Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Islets of Langerhans

Share to Models, Biological

Share to TCF Transcription Factors

Share to Transcription Factor 7-Like 2 Protein

Share to Wnt Proteins

Source

Identifiers

PMID: 20217507
DOI: 10.1007/978-90-481-3271-3_17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Wnt signaling in pancreatic islets.PMID 20217507Read ↗

Islet Specific Wnt Activation in Human Type II DiabetesSemantic proximity Read ↗

The Wnt signaling pathway effector TCF7L2 and type 2 diabetes mellitus.Semantic proximity Read ↗

The involvement of the wnt signaling pathway and TCF7L2 in diabetes mellitus: The current understanding, dispute, and perspectiveSemantic proximity Read ↗

TCF7L2 rs7903146 impairs islet function and morphology in non-diabetic individuals.Semantic proximity Read ↗

The what, where, when and how of Wnt/β-catenin signaling in pancreas developmentSemantic proximity Read ↗

Pancreatic Pericytes Support β-Cell Function in a Tcf7l2-Dependent Manner.Semantic proximity Read ↗

TCF7L2 controls insulin gene expression and insulin secretion in mature pancreatic β-cellsSemantic proximity Read ↗

Wnt signaling regulates pancreatic β cell proliferationSemantic proximity Read ↗

Tcf7l2 plays pleiotropic roles in the control of glucose homeostasis, pancreas morphology, vascularization and regeneration.Semantic proximity Read ↗

The role of transcription factor 7‐like 2 in metabolic disordersSemantic proximity Read ↗

Regulation of wingless-type MMTV integration site family (WNT) signalling in pancreatic islets from wild-type and obese mice.Semantic proximity Read ↗

TCF7L2 genetic defect and type 2 diabetes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.