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Article

Kinetic parameters for the elimination reaction catalyzed by triosephosphate isomerase and an estimation of the reaction's physiological significance.

Biochemistry - 7 May 1991

Richard J P

Abstract excerpt

Kinetic parameters for triosephosphate isomerase catalysis of the elimination reaction of an equilibrium mixture of dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (DGAP) to form methylglyoxal and phosphate ion are reported for the enzyme from rabbit muscle. Pseudo-first-order rate constants for the disappearance of substrate (kelim) were determined for reactions at [Enzyme] much greater than...

Topics

Animals
Dihydroxyacetone Phosphate
Glyceraldehyde 3-Phosphate
Kinetics
Lactoylglutathione Lyase
Muscles
Mutation
Pyruvaldehyde
Rabbits
Thiolester Hydrolases
Triose-Phosphate Isomerase

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PMID: 2021650
DOI: 10.1021/bi00232a031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2021650-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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