Analysis of algebraic weighted least-squares estimators for enzyme parameters.

doi:10.1042/bj2880533

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Article

Analysis of algebraic weighted least-squares estimators for enzyme parameters.

The Biochemical journal - 1 Dec 1992

Jones M E

Abstract excerpt

An algorithm for the least-squares estimation of enzyme parameters Km and Vmax. is proposed and its performance analysed. The problem is non-linear, but the algorithm is algebraic and does not require initial parameter estimates. On a spreadsheet program such as MINITAB, it may be coded in as few...

Topics

Algorithms
Enzymes
Genetic Variation
Kinetics
Mathematics
Poisson Distribution
Regression Analysis

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