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Article

Modelling, steady state analysis and optimization of the catalytic efficiency of the triosephosphate isomerase.

Bulletin of mathematical biology - 1 Mar 2002

Marín-Sanguino Alberto, Torres Néstor V

Abstract excerpt

In the present work we have modelled and optimized the reaction mechanism of the triose phosphate isomerase (TIM) enzyme (E.C. 5.3.1.1). For this purpose we have used an approach that combines the S-system representation within the power law formalism and linear programming techniques. By this means we have explored those rate constants whose alterations are likely to improve the catalytic efficiency of the...

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PMID: 11926119
DOI: 10.1006/bulm.2001.0276

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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