Renalase-A new understanding of its enzymatic and non-enzymatic activity and its implications for future research.

Abstract excerpt

Renalase was first described in 2005 and since then it became an object of scientific interest because of its proposed ability to catalyse circulating neurotransmitters and its promising antihypertensive effects. However, further research on the enzymatic activity of renalase did not confirm these initial findings and yielded that renalase serves to oxidize isomeric forms of β-NAD(P)H and recycle them by forming...

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