Clinical and Molecular Assessment of Patients with Lynch Syndrome and Sarcomas Underpinning the Association with MSH2 Germline Pathogenic Variants

Abstract excerpt

Lynch syndrome (LS) is a hereditary cancer-predisposing syndrome associated most frequently with epithelial tumors, particularly colorectal (CRC) and endometrial carcinomas (EC). The aim of this study was to investigate the relationship between sarcomas and LS by performing clinical and molecular characterization of patients presenting co-occurrence of sarcomas and tumors from the LS spectrum. We identified 27...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Colorectal and Anal Carcinomas
• Share to Colorectal Cancer Treatments and Studies
• Share to Genetic factors in colorectal cancer