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Article

The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity.

Development (Cambridge, England) - 1 Apr 2010

Tran Uyen, Zakin Lise, Schweickert Axel, Agrawal Raman, Döger Remziye, Blum Martin, De Robertis E M, Wessely Oliver

Abstract excerpt

The RNA-binding protein Bicaudal C is an important regulator of embryonic development in C. elegans, Drosophila and Xenopus. In mouse, bicaudal C (Bicc1) mutants are characterized by the formation of fluid-filled cysts in the kidney and by expansion of epithelial ducts in liver and pancreas. This...

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Identifiers

PMID: 20215348
DOI: 10.1242/dev.046045
PMCID: PMC2835326

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20215348-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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