Article
A piece of the human heart: variance of protein phosphorylation in left ventricular samples from end-stage primary cardiomyopathy patients.
Journal of muscle research and cell motility - 1 Dec 2009
van Dijk Sabine J, Holewijn Rozemarije A, Tebeest Anouk, Dos Remedios Cris, Stienen Ger J M, van der Velden Jolanda
Abstract excerpt
Cardiomyocyte contraction is regulated by phosphorylation of sarcomeric proteins. Throughout the heart regional and transmural differences may exist in protein phosphorylation. In addition, phosphorylation of sarcomeric proteins is altered in cardiac disease. Heterogeneity in protein phosphorylat...
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