Article
AMD and the alternative complement pathway: genetics and functional implications.
Human genomics - 21 Jun 2016
Tan Perciliz L, Bowes Rickman Catherine, Katsanis Nicholas
Abstract excerpt
Age-related macular degeneration (AMD) is an ocular neurodegenerative disorder and is the leading cause of legal blindness in Western societies, with a prevalence of up to 8 % over the age of 60, which continues to increase with age. AMD is characterized by the progressive breakdown of the macula (the central region of the retina), resulting in the loss of central vision including visual acuity. While its...
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