Article
Association of ion-channel genotype and macrocyclic lactone sensitivity traits in Haemonchus contortus.
Molecular and biochemical parasitology - 1 Jun 2010
Beech Robin, Levitt Nancy, Cambos Mathieu, Zhou Shufeng, Forrester Sean G
Abstract excerpt
Resistance to macrocyclic lactones in the strongylid parasite of sheep, Haemonchus contortus, is associated with specific alleles of several genes, including those encoding ligand-gated chloride-channels. While previous functional studies of the ion-channels encoded by these resistant alleles hav...
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