Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Left ventricular noncompaction is associated with mutations in the mitochondrial genome.

Mitochondrion - 1 Jun 2010

Tang Sha, Batra Anjan, Zhang Yu, Ebenroth Eric S, Huang Taosheng

Abstract excerpt

Left ventricular noncompaction (LVNC) is a genetically heterogeneous condition and several nuclear loci have been associated with the defect. However, they only account for a small percentage of patients. Existing evidences suggest that pathogenic mitochondrial DNA (mtDNA) mutations and consequent mitochondrial malfunction can be an important component in the etiology of LVNC. To investigate if mtDNA mutation can...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to DNA, Mitochondrial
Share to Genome, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infant, Newborn

Share to Isolated Noncompaction of the Ventricular Myocardium

Share to Mutation, Missense

Share to NADH Dehydrogenase

Share to Point Mutation

Source

Identifiers

PMID: 20211276
DOI: 10.1016/j.mito.2010.02.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Left ventricular noncompaction is associated with mutations in the mitochondrial genome.PMID 20211276Read ↗

Whole exome sequencing identifies novel candidate mutations in a Chinese family with left ventricular noncompaction.Semantic proximity Read ↗

Do mitochondria contribute to left ventricular non-compaction cardiomyopathy? New findings from myocardium of patients with left ventricular non-compaction cardiomyopathy.Semantic proximity Read ↗

Genetic Analysis of Patients with Left Ventricular Noncompaction: Identification of Novel Candidate VariantsSemantic proximity Read ↗

Recent advancements in the molecular genetics of left ventricular noncompaction cardiomyopathy.Semantic proximity Read ↗

Genetic architecture of left ventricular noncompaction in adultsSemantic proximity Read ↗

Increased Burden of Ion Channel Gene Variants Is Related to Distinct Phenotypes in Pediatric Patients With Left Ventricular Noncompaction.Semantic proximity Read ↗

Novel Genetic Triggers and Genotype-Phenotype Correlations in Patients With Left Ventricular Noncompaction.Semantic proximity Read ↗

Identification of a novel TPM1 mutation in a family with left ventricular noncompaction and sudden death.Semantic proximity Read ↗

Mitochondrial DNA variations associated with hypertrophic cardiomyopathy.Semantic proximity Read ↗

Evolutionary analyses of entire genomes do not support the association of mtDNA mutations with Ras/MAPK pathway syndromes.Semantic proximity Read ↗

Mitochondrial Mutations in Cardiovascular Diseases: Preliminary Findings.Semantic proximity Read ↗

A novel mutation in the TTN gene resulted in left ventricular noncompaction: a case report and literature review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.