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Article

Identification of a novel TPM1 mutation in a family with left ventricular noncompaction and sudden death.

Molecular genetics and metabolism - 1 Feb 2011

Chang Bo, Nishizawa Tsutomu, Furutani Michiko, Fujiki Akira, Tani Masanao, Kawaguchi Makoto, Ibuki Keijiro, Hirono Keiichi, Taneichi Hiromichi, Uese Keiichiro, Onuma Yoshiko, Bowles Neil E, Ichida Fukiko, Inoue Hiroshi, Matsuoka Rumiko, Miyawaki Toshio

Abstract excerpt

Left ventricular noncompaction (LVNC) is a cardiomyopathy morphologically characterized by 2-layered myocardium, numerous prominent trabeculations, and deep intertrabecular recesses communicating with the left ventricular cavity. The purpose of this study was to investigate patients with LVNC for...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20965760
DOI: 10.1016/j.ymgme.2010.09.009

Genes

TPM1
DTNA
LDB3
MYBPC3
MYH7
MYL2
MYL3
TNNI3
TNNT2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20965760-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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