Article
Novel Genetic Triggers and Genotype-Phenotype Correlations in Patients With Left Ventricular Noncompaction.
Circulation. Cardiovascular genetics - 1 Aug 2017
Miszalski-Jamka Karol, Jefferies John L, Mazur Wojciech, Głowacki Jan, Hu Jianhong, Lazar Monika, Gibbs Richard A, Liczko Jacek, Kłyś Jan, Venner Eric, Muzny Donna M, Rycaj Jarosław, Białkowski Jacek, Kluczewska Ewa, Kalarus Zbigniew, Jhangiani Shalini, Al-Khalidi Hussein, Kukulski Tomasz, Lupski James R, Craigen William J, Bainbridge Matthew N
Abstract excerpt
BACKGROUND: Left ventricular noncompaction (LVNC) is a genetically and phenotypically heterogeneous disease and, although increasingly recognized in clinical practice, there is a lack of widely accepted diagnostic criteria. We sought to identify novel genetic causes of LVNC and describe genotype-phenotype correlations. METHODS AND RESULTS: A total of 190 patients from 174 families with left ventricular...
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