Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Increased Burden of Ion Channel Gene Variants Is Related to Distinct Phenotypes in Pediatric Patients With Left Ventricular Noncompaction.

Circulation. Genomic and precision medicine - 1 Aug 2020

Hirono Keiichi, Hata Yukiko, Miyao Nariaki, Okabe Mako, Takarada Shinya, Nakaoka Hideyuki, Ibuki Keijiro, Ozawa Sayaka, Origasa Hideki, Nishida Naoki, Ichida Fukiko

Abstract excerpt

BACKGROUND: Left ventricular noncompaction (LVNC) is a hereditary type of cardiomyopathy. Although it is associated with high morbidity and mortality, the related ion channel gene variants in children have not been fully investigated. This study aimed to elucidate the ion channel genetic landscape of LVNC and identify genotype-phenotype correlations in a large Japanese cohort. METHODS: We enrolled 206 children...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arrhythmias, Cardiac
Share to Echocardiography

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Defects, Congenital

Share to Ion Channels

Share to Isolated Noncompaction of the Ventricular Myocardium

Share to Proportional Hazards Models

Share to Survival Analysis

Share to Ventricular Function, Left

Source

Identifiers

PMID: 32600061
DOI: 10.1161/CIRCGEN.119.002940

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased Burden of Ion Channel Gene Variants Is Related to Distinct Phenotypes in Pediatric Patients With Left Ventricular Noncompaction.PMID 32600061Read ↗

A Wide and Specific Spectrum of Genetic Variants and Genotype-Phenotype Correlations Revealed by Next-Generation Sequencing in Patients with Left Ventricular Noncompaction.Semantic proximity Read ↗

Genetic Profile of Left Ventricular Noncompaction Cardiomyopathy in Children—A Single Reference Center ExperienceSemantic proximity Read ↗

Determination of Genotype and Phenotypes in Pediatric Patients With Biventricular Noncompaction.Semantic proximity Read ↗

Genetic architecture of left ventricular noncompaction in adultsSemantic proximity Read ↗

Multiple genetic variants in adolescent patients with left ventricular noncompaction cardiomyopathy.Semantic proximity Read ↗

Molecular analysis of dilated and left ventricular noncompaction cardiomyopathies in Egyptian children.Semantic proximity Read ↗

Systematic large-scale assessment of the genetic architecture of left ventricular noncompaction reveals diverse etiologiesSemantic proximity Read ↗

Novel Genetic Triggers and Genotype-Phenotype Correlations in Patients With Left Ventricular Noncompaction.Semantic proximity Read ↗

Genotype-Phenotype Insights of Inherited Cardiomyopathies-A Review.Semantic proximity Read ↗

Genotype‐Positive Status Is Associated With Poor Prognoses in Patients With Left Ventricular Noncompaction CardiomyopathySemantic proximity Read ↗

Phenotype/Genotype Relationship in Left Ventricular Noncompaction: Ion Channel Gene Mutations Are Associated With Preserved Left Ventricular Systolic Function and Biventricular Noncompaction: Phenotype/Genotype of Noncompaction.Semantic proximity Read ↗

Electrophysiological phenotyping of left ventricular noncompaction cardiomyopathy in pediatric populations: A systematic review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.