Article
Collagen XXVII organises the pericellular matrix in the growth plate.
PloS one - 1 Jan 2011
Plumb Darren A, Ferrara Laila, Torbica Tanja, Knowles Lynnette, Mironov Aleksandr, Kadler Karl E, Briggs Michael D, Boot-Handford Raymond P
Abstract excerpt
In order to characterise the function of the novel fibrillar type XXVII collagen, a series of mice expressing mutant forms of the collagen were investigated. Mice harboring a glycine to cysteine substitution in the collagenous domain were phenotypically normal when heterozygote and displayed a mild disruption of growth plate architecture in the homozygous state. Mice expressing an 87 amino acid deletion in the...
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