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Article

Progress and opportunities in molecular pathological epidemiology of colorectal premalignant lesions.

The American journal of gastroenterology - 1 Aug 2014

Lochhead Paul, Chan Andrew T, Giovannucci Edward, Fuchs Charles S, Wu Kana, Nishihara Reiko, O'Brien Michael, Ogino Shuji

Abstract excerpt

Molecular pathological epidemiology (MPE) is an integrative molecular and population health science that addresses the molecular pathogenesis and heterogeneity of disease processes. The MPE of colonic and rectal premalignant lesions (including hyperplastic polyps, tubular adenomas, tubulovillous adenomas, villous adenomas, traditional serrated adenomas, sessile serrated adenomas/sessile serrated polyps, and...

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Source

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Identifiers

PMID: 24935274
DOI: 10.1038/ajg.2014.153
PMCID: PMC4125459

Genes

BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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