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Article

Hepatic metabolism and transporter gene variants enhance response to rosuvastatin in patients with acute myocardial infarction: the GEOSTAT-1 Study.

Circulation. Cardiovascular genetics - 1 Jun 2010

Bailey Kristian M, Romaine Simon P R, Jackson Beryl M, Farrin Amanda J, Efthymiou Maria, Barth Julian H, Copeland Joanne, McCormack Terry, Whitehead Andrew, Flather Marcus D, Samani Nilesh J, Nixon Jane, Hall Alistair S, Balmforth Anthony J

Abstract excerpt

BACKGROUND: Pharmacogenetics aims to maximize benefits and minimize risks of drug treatment. Our objectives were to examine the influence of common variants of hepatic metabolism and transporter genes on the lipid-lowering response to statin therapy. METHODS AND RESULTS: The Genetic Effects On ST...

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 2
Share to Cytochrome P-450 CYP3A

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydroxymethylglutaryl-CoA Reductase Inhibitors

Share to Liver-Specific Organic Anion Transporter 1

Share to Organic Anion Transporters

Share to Rosuvastatin Calcium

Share to Simvastatin

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Source

Identifiers

PMID: 20207952
DOI: 10.1161/CIRCGENETICS.109.898502

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20207952-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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