Article
IL-10 and TNF-beta gene polymorphisms have no major influence on lactate levels after cardiac surgery.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery - 1 Jul 2006
Riha Hynek, Hubacek Jaroslav A, Poledne Rudolf, Kellovsky Pavel, Brezina Ales, Pirk Jan
Abstract excerpt
OBJECTIVE: Lactate levels after cardiac surgery are influenced by different proinflammatory (TNF, IL-6, IL-8) and anti-inflammatory (IL-10) cytokines. The goal of the study was to determine the relationship between polymorphism in the IL-10 (-1082G/A) and TNF-beta (+252G/A) genes and lactate levels in patients after cardiac surgery. METHODS: We performed prospective observational study in 168 consecutive adult...
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