Article
"Zero-length" dimers of ribonuclease A: further characterization and no evidence of cytotoxicity.
Bioconjugate chemistry - 21 Apr 2010
Vottariello Francesca, Costanzo Chiara, Gotte Giovanni, Libonati Massimo
Abstract excerpt
"Zero-length" dimers of ribonuclease A, a novel type of dimers formed by two RNase A molecules bound to each other through a zero-length amide bond [Simons, B. L., et al. (2007) Proteins 66, 183-195], were further characterized and tested for their possible in vitro cytotoxic activity. Results obtained are the following. Besides dimers, also trimers and higher oligomers could be identified among the products of...
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