Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of residues within ligand‐binding domain 1 (LBD1) of the <i>Borrelia burgdorferi</i> OspC protein required for function in the mammalian environment

1 Mar 2010

Abstract excerpt

Borrelia burgdorferi outer surface protein C (ospC) is required for the establishment of infection in mammals. However, its precise function remains controversial. The biologically active form of OspC appears to be a homodimer. Alpha helix 1 and 1' of the apposing monomers form a solvent-accessible pocket at the dimeric interface that presents a putative ligand-binding domain (LBD1). Here we employ site-directed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Insect symbiosis and bacterial influences
Share to Mosquito-borne diseases and control
Share to Vector-borne infectious diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20199597
DOI: 10.1111/j.1365-2958.2010.07103.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of residues within ligand‐binding domain 1 (LBD1) of the <i>Borrelia burgdorferi</i> OspC protein required for function in the mammalian environmentPMID 20199597Read ↗

Delineating the Requirement for the <i>Borrelia burgdorferi</i> Virulence Factor OspC in the Mammalian HostSemantic proximity Read ↗

The long strange trip of Borrelia burgdorferi outer‐surface protein CSemantic proximity Read ↗

Identification of an ospC operator critical for immune evasion of Borrelia burgdorferi.Semantic proximity Read ↗

Outer surface protein C is a dissemination-facilitating factor of Borrelia burgdorferi during mammalian infection.Semantic proximity Read ↗

Outer-surface protein C of the Lyme disease spirochete: a protein induced in ticks for infection of mammals.Semantic proximity Read ↗

Four clones of Borrelia burgdorferi sensu stricto cause invasive infection in humans.Semantic proximity Read ↗

<i>Borrelia burgdorferi</i> adhesins identified using <i>in vivo</i> phage displaySemantic proximity Read ↗

<i>Borrelia</i>Outer Membrane Surface Proteins and Transmission Through the TickSemantic proximity Read ↗

Strain-specific joint invasion and colonization by Lyme disease spirochetes is promoted by outer surface protein C.Semantic proximity Read ↗

Comprehensive seroprofiling of sixteen B. burgdorferi OspC: implications for Lyme disease diagnostics design.Semantic proximity Read ↗

Outer surface protein B is critical for Borrelia burgdorferi adherence and survival within Ixodes ticks.Semantic proximity Read ↗

Borrelia burgdorferi OspC protein required exclusively in a crucial early stage of mammalian infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.