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Article

Four clones of Borrelia burgdorferi sensu stricto cause invasive infection in humans.

Infection and immunity - 1 Jul 1999

Seinost G, Dykhuizen D E, Dattwyler R J, Golde W T, Dunn J J, Wang I N, Wormser G P, Schriefer M E, Luft B J

Abstract excerpt

Lyme disease begins at the site of a tick bite, producing a primary infection with spread of the organism to secondary sites occurring early in the course of infection. A major outer surface protein expressed by the spirochete early in infection is outer surface protein C (OspC). In Borrelia burgdorferi sensu stricto, OspC is highly variable. Based on sequence divergence, alleles of ospC can be divided into 21...

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Identifiers

PMID: 10377134
DOI: 10.1128/IAI.67.7.3518-3524.1999
PMCID: PMC116539

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