Article
Outer-surface protein C of the Lyme disease spirochete: a protein induced in ticks for infection of mammals.
Proceedings of the National Academy of Sciences of the United States of America - 2 Mar 2004
Grimm Dorothee, Tilly Kit, Byram Rebecca, Stewart Philip E, Krum Jonathan G, Bueschel Dawn M, Schwan Tom G, Policastro Paul F, Elias Abdallah F, Rosa Patricia A
Abstract excerpt
Environmentally responsive synthesis of surface proteins represents a hallmark of the infectious cycle of the Lyme disease agent, Borrelia burgdorferi. Here we created and analyzed a B. burgdorferi mutant lacking outer-surface protein C (OspC), an abundant Osp that spirochetes normally synthesize...
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