Article
Analysis of complex relationships between age, p53, epidermal growth factor receptor, and survival in glioblastoma patients.
Cancer research - 1 Feb 2001
Simmons M L, Lamborn K R, Takahashi M, Chen P, Israel M A, Berger M S, Godfrey T, Nigro J, Prados M, Chang S, Barker F G, Aldape K
Abstract excerpt
Glioblastoma multiforme (GBM) carries a dismal prognosis. However, a range of survival times exists, and parameters that define prognostic groups may help to optimize treatment. To identify such prognostic groups, we analyzed tumor tissue from 110 cases of newly diagnosed GBM from two clinical protocols. Similar to other studies, we found no association of epidermal growth factor receptor (EGFR) overexpression...
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