Article
Variation in the gene encoding the serotonin transporter is associated with a measure of sociopathy in alcoholics.
Addiction biology - 1 Jan 2011
Herman Aryeh I, Conner Tamlin S, Anton Raymond F, Gelernter Joel, Kranzler Henry R, Covault Jonathan
Abstract excerpt
The present study examined the association between a measure of sociopathy and 5-HTTLPR genotype in a sample of individuals from Project MATCH, a multi-center alcohol treatment trial. 5-HTTLPR, an insertion-deletion polymorphism in SLC6A4, the gene encoding the serotonin transporter protein, results in functionally distinct long (L) and short (S) alleles. The S allele has been associated with a variety of...
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