Article
Serotonin transporter protein gene polymorphism and personality measures in African American and European American subjects.
The American journal of psychiatry - 1 Oct 1998
Gelernter J, Kranzler H, Coccaro E F, Siever L J, New A S
Abstract excerpt
OBJECTIVE: The SLC6A4 locus encodes the serotonin transporter, which in turn mediates the synaptic inactivation of the neurotransmitter serotonin. A polymorphism located in the 5' promoter region of the gene is associated with altered transcriptional activity of SLC6A4; an earlier study reported...
Topics
- Adult
- Black People
- Carrier Proteins
- Female
- Gene Frequency
- Genotype
- Humans
- Introns
- Male
- Membrane Glycoproteins
- Membrane Transport Proteins
- Nerve Tissue Proteins
- Personality
- Personality Disorders
- Polymorphism, Genetic
- Promoter Regions, Genetic
- Serotonin
- Serotonin Plasma Membrane Transport Proteins