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Article

Human liver expression of CYP2C8: gender, age, and genotype effects.

Drug metabolism and disposition: the biological fate of chemicals - 1 Jun 2010

Naraharisetti Suresh Babu, Lin Yvonne S, Rieder Mark J, Marciante Kristin D, Psaty Bruce M, Thummel Kenneth E, Totah Rheem A

Abstract excerpt

Research investigating CYP2C8 as a drug-metabolizing enzyme has gained momentum over the past few years. CYP2C8 is estimated to oxidatively metabolize approximately 5% of therapeutically prescribed drugs. It is polymorphically expressed, and several single nucleotide polymorphisms have been ident...

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Identifiers

PMID: 20190184
DOI: 10.1124/dmd.109.031542
PMCID: PMC2879956

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20190184-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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