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Article

Carbamate transport in carbamoyl phosphate synthetase: a theoretical and experimental investigation.

Journal of the American Chemical Society - 24 Mar 2010

Lund Liliya, Fan Yubo, Shao Qiang, Gao Yi Qin, Raushel Frank M

Abstract excerpt

The transport of carbamate through the large subunit of carbamoyl phosphate synthetase (CPS) from Escherichia coli was investigated by molecular dynamics and site-directed mutagenesis. Carbamate, the product of the reaction involving ATP, bicarbonate, and ammonia, must be delivered from the site...

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Identifiers

PMID: 20187643
DOI: 10.1021/ja910441v
PMCID: PMC2847351

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20187643-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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