Article
Regulation of an Escherichia coli/mammalian chimeric carbamoyl-phosphate synthetase.
The Journal of biological chemistry - 20 Nov 1998
Sahay N, Guy H I, Liu X, Evans D R
Abstract excerpt
Carbamoyl-phosphate synthetase (CPSase) consists of a 120-kDa synthetase domain (CPS) that makes carbamoyl phosphate from ATP, bicarbonate, and ammonia usually produced by a separate glutaminase domain. CPS is composed of two subdomains, CPS.A and CPS.B. Although CPS.A and CPS.B have specialized...
Topics
- Adenosine Triphosphate
- Allosteric Regulation
- Ammonia
- Animals
- Bicarbonates
- Carbamoyl-Phosphate Synthase (Ammonia)
- Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing)
- Carbamyl Phosphate
- Escherichia coli
- Glutamine
- Ligands
- Mammals
- Models, Molecular
- Mutation
- Phosphoribosyl Pyrophosphate
- Recombinant Fusion Proteins
- Sequence Deletion