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A Genome-wide screen identifies frequently methylated genes in haematological and epithelial cancers

25 Feb 2010

Abstract excerpt

BACKGROUND: Genetic as well as epigenetic alterations are a hallmark of both epithelial and haematological malignancies. High throughput screens are required to identify epigenetic markers that can be useful for diagnostic and prognostic purposes across malignancies. RESULTS: Here we report for the first time the use of the MIRA assay (methylated CpG island recovery assay) in combination with genome-wide CpG...

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PMID: 20184741
DOI: 10.1186/1476-4598-9-44

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