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Article

DNA methylation analysis of bone marrow cells at diagnosis of acute lymphoblastic leukemia and at remission.

PloS one - 1 Jan 2012

Nordlund Jessica, Milani Lili, Lundmark Anders, Lönnerholm Gudmar, Syvänen Ann-Christine

Abstract excerpt

To detect genes with CpG sites that display methylation patterns that are characteristic of acute lymphoblastic leukemia (ALL) cells, we compared the methylation patterns of cells taken at diagnosis from 20 patients with pediatric ALL to the methylation patterns in mononuclear cells from bone marrow of the same patients during remission and in non-leukemic control cells from bone marrow or blood. Using a...

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Share to Bone Marrow Cells
Share to CpG Islands
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Gene Expression Regulation, Neoplastic

Share to Leukocytes, Mononuclear

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Share to Remission Induction

Source

Open in PubMed Open full text

Identifiers

PMID: 22493696
DOI: 10.1371/journal.pone.0034513
PMCID: PMC3321015

Genes

CPNE7
EYA4
LGALS8
RYR3
UQCRFS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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