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Article

Proliferation of Human Glioblastoma Stem Cells Occurs Independently of Exogenous Mitogens

23 Apr 2009

Abstract excerpt

Primary glial tumors of the central nervous system, most commonly glioblastoma multiforme (GBM), are aggressive lesions with a dismal prognosis. Despite identification and isolation of human brain tumor stem cells (BTSCs), characteristics that distinguish BTSCs from neural stem cells remain to be elucidated. We cultured cells isolated from gliomas, using the neurosphere culture system, to understand their growth...

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PMID: 19544433
DOI: 10.1002/stem.98

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