Article
Expression profile of cancer-related genes in human adult bone marrow-derived neural stemlike cells highlights the need for tumorigenicity study.
Journal of neuroscience research - 1 Nov 2007
Zhu Rusen, Xu Ruxiang, Jiang Xiaodan, Cai Yingqian, Zou Yuxi, Du Mouxuan, Qin Lingsha
Abstract excerpt
Human adult bone marrow-derived neural stemlike cells (MDNSCs) may serve as ideal seed cells for cell replacement therapy for human neurological disorders and injuries. However, the long-term safety of this cell population after transplantation must be thoroughly explored before clinical application, and tumorigenicity is a major concern. In this study, we generated MDNSCs capable of forming neurospherelike...
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