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Parallel inhibition of cell growth and induction of cell migration and invasion in breast cancer cells by bone morphogenetic protein 4.

Breast cancer research and treatment - 1 Nov 2010

Ketolainen Johanna M, Alarmo Emma-Leena, Tuominen Vilppu J, Kallioniemi Anne

Abstract excerpt

Bone morphogenetic proteins (BMP) are extracellular signaling molecules that belong to the transforming growth factor β (TGFβ) superfamily. Bone morphogenetic proteins have diverse roles during development where they regulate proliferation, differentiation, and apoptosis in many different cell types by modulating the transcription of specific target genes. BMPs have also been implicated in both promotion and...

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Source

Identifiers

PMID: 20182795
DOI: 10.1007/s10549-010-0808-0

Genes

BMP4

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Parallel inhibition of cell growth and induction of cell migration and invasion in breast cancer cells by bone morphogenetic protein 4.PMID 20182795Read ↗

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A Comprehensive Review Exploring the Role of Bone Morphogenetic Proteins [BMP]: Biological MechanismsSemantic proximity Read ↗

BMP7 influences proliferation, migration, and invasion of breast cancer cells.Semantic proximity Read ↗

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BMP-3b suppresses proliferation, migration, invasion, and TGF-β 1/Smad3 signaling in breast cancer cellsSemantic proximity Read ↗

Bone Morphogenetic Protein Signaling in Cancer; Some Topics in the Recent 10 YearsSemantic proximity Read ↗

The Dual Role of Bone Morphogenetic Proteins in CancerSemantic proximity Read ↗

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