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BMP4 enhances anoikis resistance and chemoresistance of breast cancer cells through canonical BMP signaling

4 Oct 2021

Abstract excerpt

Bone morphogenetic proteins (BMPs) regulate cell fate during development and mediate cancer progression. In this study, we investigated the role of BMP4 in proliferation, anoikis resistance, metastatic migration, and drug resistance of breast cancer cells. We utilized breast cancer cell lines and clinical samples representing different subtypes to understand the functional effect of BMP4 on breast cancer. The BMP...

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PMID: 34608584
DOI: 10.1007/s12079-021-00649-9

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