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Article

Promoter DNA hypermethylation in gastric biopsies from subjects at high and low risk for gastric cancer.

International journal of cancer - 1 Dec 2010

Schneider Barbara G, Peng Dun-Fa, Camargo M Constanza, Piazuelo M Blanca, Sicinschi Liviu A, Mera Robertino, Romero-Gallo Judith, Delgado Alberto G, Bravo Luis E, Wilson Keith T, Peek Richard M, Correa Pelayo, El-Rifai Wael

Abstract excerpt

Gene promoter CpG island hypermethylation is associated with Helicobacter pylori (H. pylori) infection and may be an important initiator of gastric carcinogenesis. To examine factors influencing methylation, we utilized bisulfite Pyrosequencing® technology for quantitative analysis of promoter DNA methylation in RPRM, APC, MGMT and TWIST1 genes using DNA from 86 gastric biopsies from Colombian residents of areas...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20178103
DOI: 10.1002/ijc.25274
PMCID: PMC2916942

Genes

RPRM
TWIST1
MGMT
APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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