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Article

Influence of IL1B polymorphism on CpG island hypermethylation in Helicobacter pylori-infected gastric cancer.

Virchows Archiv : an international journal of pathology - 1 Jun 2010

Yoo Eun Joo, Park Seog-Yun, Cho Nam-Yun, Kim Nayoung, Lee Hye Seung, Kim Donguk, Kang Gyeong Hoon

Abstract excerpt

Helicobacter pylori infection can induce aberrant CpG island hypermethylation in gastric mucosal epithelial cells. Single nucleotide polymorphisms of proinflammatory cytokine genes encoding for interleukin 1B (IL1B), IL6, and IL8 have been demonstrated to be associated with an increased risk of gastric cancer. To identify the influence of host genetic factors in CpG island hypermethylation induced by H. pylori...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20405297
DOI: 10.1007/s00428-010-0918-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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