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Article

Identifying the rules of engagement enabling leukocyte rolling, activation, and adhesion.

PLoS computational biology - 19 Feb 2010

Tang Jonathan, Hunt C Anthony

Abstract excerpt

The LFA-1 integrin plays a pivotal role in sustained leukocyte adhesion to the endothelial surface, which is a precondition for leukocyte recruitment into inflammation sites. Strong correlative evidence implicates LFA-1 clustering as being essential for sustained adhesion, and it may also facilit...

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Share to Cell Adhesion
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lymphocyte Function-Associated Antigen-1

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Source

Open in PubMed Open full text

Identifiers

PMID: 20174606
DOI: 10.1371/journal.pcbi.1000681
PMCID: PMC2824748

Genes

ICAM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20174606-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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