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Article

Dynamics of in silico leukocyte rolling, activation, and adhesion

19 Feb 2007

Abstract excerpt

BACKGROUND: We present a multilevel, agent based, in silico model that represents the dynamics of rolling, activation, and adhesion of individual leukocytes in vitro. Object-oriented software components were designed, verified, plugged together, and then operated in ways that represent the molecular and cellular mechanisms believed responsible for leukocyte rolling and adhesion. The result is an in silico...

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PMID: 17408504
DOI: 10.1186/1752-0509-1-14

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